Yaponiyaning Mie universiteti tadqiqot guruhi erta zebrafish embrionlarini (urug'lantirilgandan keyin bir necha soat o'tgach) 278 nm UVC nurlanishi bilan xavfsiz nurlanishi mumkinligini aniqladi.
260 nm atrofida UVC{0}}LEDlar sterilizatsiya uchun ishlatiladi, chunki ular bakteriya va viruslardan DNK shikastlanishini keltirib chiqaradi va inaktiv qiladi. Hozirgi tadqiqotlarning aksariyati to'lqin uzunligi 240 nm (207 nm, 222 nm, 233 nm) dan past bo'lgan UVC ning yangi koronavirusni o'ldirishga ta'siriga qaratilgan. Biroq, organizmlarning toksikligi, xavfsizligi va 280 nm atrofida UVC nurlanishiga reaktsiyasi bo'yicha bir nechta tadqiqotlar mavjud.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Ushbu mavzu bo'yicha tadqiqot natijalari inson tanasiga tatbiq etiladigan UVC-LEDning xavfsizligi uchun ilmiy asos bo'lib xizmat qiladi. Shu bilan birga, tadqiqot guruhi UVC bakteriya va viruslarni, shu jumladan koronavirusni dezinfeksiya qilish, shuningdek, akvakulturada dezinfeksiya qilish uchun mos ekanligini aniqladi.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
GMKJ LED texnologiyasi sog'lom va aqlli yorug'lik manbalari bilan chuqur shug'ullanadi, bozorni UVA UVB UVC LED, infraqizil IR LED VCSEL mahsulotlari va yechimlari bilan ta'minlaydi va mahalliy va xorijiy yuzlab{0}}yuqori sifatli hamkorlarga ega. sog'lom va aqlli hayotni yaratish uchun yorug'lik texnologiyasidan foydalanishni birgalikda rag'batlantirish uchun bozorlar. sabab.
